1-Hour Bundle for Sepsis: SSC 2018 Update

SSC Hour-1 Bundle

The most important change in the revision of the SSC bundles is that the 3-h and 6-h bundles have been combined into a single “hour-1 bundle” with the explicit intention of beginning resuscitation and management immediately.

• Measure lactate level. If initial lactate > 2mmol/L, it should be re-measured within 2−4 h to guide resuscitation to normalize lactate. 

• Obtain blood cultures prior to administration of antibiotics.

• Administer broad-spectrum antibiotics.

• Rapidly administration of 30 mL/kg crystalloid for hypotension or lactate ≥ 4 mmol/L. This bolus should be completed within 3 hours.

• Apply vasopressors if patient is hypotensive during or after fluid resuscitation to maintain MAP ≥ 65 mmHg.

References

The Surviving Sepsis Campaign Bundle: 2018 Update 

SSC Hour-1 Bundle: Infograph 

Surviving Sepsis Guidelines 2016

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敗血症 一小時組套：2018 SSC 更新摘要

1-h bundles 取代過去的 3-h and 6-h bundles

• 每 2-4 小時 驗 Lactate level 直到正常
• Blood cultures
• 廣效性抗生素
• 3小時內 給完 Crystalloid fluid 30 ml/kg
• 升壓劑 維持 MAP ≥ 65 mmHg